Store round roast in its original packaging in the coldest part of the refrigerator, where it will keep for three to four days. It may be frozen in this packaging for up to two weeks. For longer storage, wrap the roast in heavy-duty aluminum foil, freezer paper, or freezer bags. Round roast will keep six to twelve months in the freezer. Defrost the roast in the refrigerator, allowing 24 to 48 hours, depending on size. Cook as soon as possible after defrosting.